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IIT-Roorkee research! Drug investigative for antibiotic resistance

by Live India
IIT-Roorkee New Discovery

IIT-Suorkee New Discovery: This discovery of IIT-Roorkee is not only an important achievement for the medical world, but it is also a solid step towards dealing with the problem of increasing antibiotic resistance globally.

IIT-Roorkee New Discovery: Researchers at the Indian Institute of Technology (IIT) Roorkee have discovered a new drug that can help in dealing with the increasing immunity of bacteria towards antibiotic resistance. This drug works closely with a particular antibiotic “meropename” and deadly bacteria KPC-2-producing Klebsiella pneumoniae Can prove to be effective against, which has been included in its top priority threats by the World Health Organization (WHO).

New discovery and its importance

IIT-Roorkee New Discovery

The team of researchers has prepared a unique molecule, which can treat infections with meropenames that have been difficult to cure with drugs till now. This discovery is also special because Klebsiella pneumoniae For example, “superbugs” neutralize many existing antibiotics, which increases the risk of severe infection. This research has been published in the prestigious Journal of Medicinal Chemistry and it is expected that it will contribute significantly to the development of new drugs to fight superbugs in the future.

How this medicine works

The newly discovered drug belongs to the “β-lactamase inhibitor” class. It prevents the enzymes of bacteria that break and neutralize life saving antibiotics. This molecule called “Compound 3B” is extremely specific, is safe for human cells and is more effective in killing bacteria together with meropename. In the tests conducted on laboratory and animals, this drug reduced the lung infection to a great extent.

Researchers’ opinion

According to Ranjan Pathania, Principal of IIT-Roorkee’s Biochemine and Bio-Engineering Department, “This discovery is an expectation for the world’s biggest health challenges like Antimicrobial Resistance. Our compound neutralizes the resistance of bacteria and gives excellent results in pre-preching models.” Institute director K.K. Pant says, “When antibiotic resistance is becoming a threat to the global health system, such innovations not only raise new expectations of treatment but also establish India on the advance front of biomedical research.”

This discovery of IIT-Roorkee is not only an important achievement for the medical world, but it is also a solid step towards dealing with the problem of increasing antibiotic resistance globally. In the coming time, successful clinical tests of this drug can make it a strong weapon to fight infections worldwide.

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